This manual describes ten seminars oriented to provide at-risk youth with the knowledge needed to improve their life skills, perceptions of life as also those of society. It profits from the capacity that sports have to create a sense of support, belonging and loyalty which in turn encourage participants to collaborate, understand and tolerate individuals from different backgrounds. By changing mentalities through education, “Line up, Live up” builds on previous UN experiences in developing and implementing an evidence-based crime, violence and drug use prevention program. The seminars are designed to be accessible and easy to put into place as there’s no need for complex or expensive equipment. It is also desirable to include youth from all genders, sexual orientations, socio-economical backgrounds and cultures in order to create from the beginning an atmosphere of tolerance and empathy.